Medicine Head formed in Stafford in 1968, and came to prominence when championed by influential DJ John Peel, who signed them to his Dandelion record label.

The group recorded six original albums, the opening trio of which were on 'Dandelion'. That label enjoyed its only UK singles chart hit when "(And The) Pictures in the Sky" reached number 22 in 1971. Despite consistent touring, often as support to acts with larger commercial appeal, Medicine Head failed to place an album on the UK album chart.

They went through line-up changes with their largely backing personnel, but did achieve a total of four hit singles, the best-known of which are "One and One is One" (No. 3, 1973) and "Rising Sun" (No. 11, 1973). At various times the line-up also included Tony Ashton, formerly of Ashton, Gardner and Dyke, and Keith Relf, the former Yardbirds vocalist.

Their later recordings were released on the Polydor record label. Two Man Band (1976) was their last album, and Medicine Head finally folded in 1977..

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