The Hombres were a Memphis, Tennessee band that formed in 1966 with Gary Wayne McEwen on guitar, B.B. Cunningham on the electric organ (brother of Bill Cunningham of The Box Tops), Jerry Lee Masters on bass and John Will Hunter (died 1976) on the drums.

The Hombres' "Let It Out (Let It All Hang Out)" is included on the soundtrack of the Cameron Crowe film, Elizabethtown. It has also been used in an advertising campaign for Foster's Lager.

The origin of the other bizarre lyrics in this song is presumably from the songwriters, but the spoken introduction – "A preachment, dear friend, you are about to receive on John Barleycorn, nicotine and the temptations of Eve" – goes all the way back to 1947, when they served to introduce a song that was every bit as strange for its era as this one was in 1967: "Cigareetes, Whusky and Wild Wild Women" by Red Ingle and His Natural Seven.

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